Cardiovascular Clinical Sciences (CCS) and SCIRENT, full-service cardiovascular CROs specializing in heart failure research, have established a strategic partnership to seamlessly execute clinical studies across North America and Europe. Together, we offer a strong network of pre-qualified high-performing research sites, comprehensive regulatory consulting, and submissions services combined with deep medical expertise supporting clinical trial design and execution.

Meet us at

ESC Heart Failure 2023

CCS Leadership

Dr. Marvin Kostam

Chief Scientific Officer

Dr. Konstam has served as chief scientific officer since CCS’ founding in 1997, bringing over 30 years experience in clinical research to his role. He is currently chief physician executive of the Cardiovascular Center at Tufts Medical Center and professor of medicine at Tufts University School of Medicine. Dr. Konstam combines vast regulatory experience on FDA advisory committees with leadership in both industry and academic clinical research. He is author of numerous publications.

Photo of Dr. James Udelson, Medical Director of a Cardiovascular Clinical Research Organization

Dr. James Udelson

Chief Medical Officer

Dr. Udelson has served as chief medical officer since CCS’ founding in 1997, bringing over 30 years experience in clinical research to his role. He is chief of cardiology and director of nuclear cardiology at Tufts Medical Center as well as professor of medicine and radiology at Tufts University School of Medicine with various industry relevant  publications.

SCIRENT Leadership

Hans-Dirk Düngen, PhD, MD, MBA, SCIRENT CEO and Scientific Director

Dr. Hans-Dirk Duengen PhD, MD, MBA

CEO and Scientific Director

Dr. Duengen is the founder and CEO of. He has collected a wealth of national and international experience in initiating and executing clinical trials as a senior cardiologist at the Charité University Hospital Berlin. Also, he is the author of numerous scientific publications


Dr. Maximilian Posch, MD 

Chief Medical Officer

Dr. Posch has a strong background in academic and industry-driven research. As a clinician of internal medicine and clinical pharmacology, he has profound expertise in early phase clinical trials and cardiovascular research. In his career, he conducted more than 200 trials and co-authored numerous peer-reviewed publications.

CCS & SCIRENT Patient recruitment experience & access

Heart Failure
(Including HFrEF, HFpEF and ADHF)
Chronic Myocarditis
Dilative and Hypertrophic Cardiomyopathy
Valvular Disease

Lipid Disorders & Hypertension

Pulmonary Arterial Hypertension
Acute Ischemic Stroke
Atherosclerosis & CAD
1 %

Cardiovascular studies in a wide range of Patient profiles

> 1

Sites across North America and Europe

1 studies

Average of 2 HF studies per year since 1997

0 patients

per month at leading sites

For more Information please get in touch with our team

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